Acute effects of growth hormone on vascular function in human subjects.

What Was Tested

This randomized controlled trial looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

GH is involved in the long-term regulation of peripheral vascular resistance and vascular reactivity.

The researchers determined whether GH plays a role in the acute regulation of vascular function in humans.

Who Took Part

The age groups tagged for this paper are adults, both men and women.

How the Study Was Run

The design is described as randomized, double-blind, placebo-controlled and parallel-group.

The participants were allocated by chance, so the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group and the comparison group should start out alike.

As a double-blind Exogenous HGH, sermorelin & older GHRPs (why they're passed over) study, the assignments were hidden from both participants and investigators until the end.

The comparison arm used a placebo, so changes seen with Exogenous HGH, sermorelin & older GHRPs (why they're passed over) could be set against what happens without it.

Groups ran in parallel: each of the participants stayed in one arm throughout.

What Was Measured

Forearm blood flow (FBF), vascular resistance, and nitric oxide (NO) production were monitored during a 4-h infusion of GH into the brachial artery at a rate chosen to raise local GH to stress levels (approximately 40 ng/ml).

The subject headings attached to it are Acetylcholine, Blood Vessels, Brachial Artery, Forearm, Growth Hormone, Injections, Intra-Arterial and Nitric Oxide.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

The publication is from 2003 (The Journal of clinical endocrinology and metabolism), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.