← Human Trials & Peer-Reviewed Studies
Safety and immunoenhancing effect of a Chlorella-derived dietary supplement in healthy adults undergoing influenza vaccination: randomized, double-blind, placebo-controlled trial.
Plain-language guide to PMID 12874157 (2003): double-blind randomized controlled trial of Adjuvants, Immunologic in 124 adults.
Key Facts
- PMID
- 12874157
- Journal
- CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
- Year
- 2003
- Study type
- Randomized Controlled Trial
- Authors
- Halperin SA et al. (5 authors)
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Adjuvants, Immunologic, published as a randomized controlled trial.
The researchers evaluated the effect of an oral dietary supplement derived from the edible microalga Chlorella pyrenoidosa on immune response after influenza vaccination.
Who Took Part
According to the abstract, 124 adults were involved.
By PubMed's age tags, the people studied were middle-aged adults, older adults and people over 80, both men and women.
The researchers obtained serum specimens to measure hemagglutination inhibition titres before and 7 and 21 days after vaccination.
How the Study Was Run
The researchers set it up as a randomized, double-blind and placebo-controlled study.
The adults were allocated by chance, so the Adjuvants, Immunologic group and the comparison group should start out alike.
Blinding on both sides kept the adults and researchers unaware of who received Adjuvants, Immunologic.
The comparison arm used a placebo, so changes seen with Adjuvants, Immunologic could be set against what happens without it.
What Was Measured
The researchers evaluated the effect of an oral dietary supplement derived from the edible microalga Chlorella pyrenoidosa on immune response after influenza vaccination.
Topics PubMed links to this paper include Adjuvants, Immunologic, Antibodies, Viral, Chlorella, Dietary Supplements, Influenza Vaccines, Plant Extracts and Vaccination.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Adjuvants, Immunologic in 124 adults.
Its findings take up roughly 8 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2003 (CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne), a journal based in Canada.
More context: all human trials.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.