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[Copper ion electrochemistry in treatment of bleeding and prolapse due to hemorrhoid, experimental and clinical studies]
Plain-language guide to PMID 12899796 (2003): controlled clinical trial study of Copper (Supplement) in 202 patients.
Key Facts
- PMID
- 12899796
- Journal
- Zhonghua yi xue za zhi
- Year
- 2003
- Study type
- Controlled Clinical Trial
- Authors
- Li DB et al. (10 authors)
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Copper (Supplement), published as a controlled clinical trial.
To observe the effect of copper ion electrochemistry (CIE) in treatment of bleeding and prolapse due to hemorrhoid.
Tissue specimens of rabbit muscle and dog anus mucosa were collected to examine the copper ion concentration.
Who Took Part
According to the abstract, 202 patients were involved.
By PubMed's age tags, the people studied were adults, middle-aged adults and older adults, both men and women.
Routine hemostasis was used at one side (control side) and CIE was used on the opposite side (experimental side).
A copper needle was inserted into each pile to the depth of 10 - 15 mm for 4'40" (with the mean number of treated points of 9.8) upon 202 patients suffering from bleeding due to hemorrhoid, 79 with inner hemorrhoids and 123 patients with mixed hemorrhoids (experimental group).
How the Study Was Run
Bleeding was caused at several points on the sacrospinal muscles of 26 rabbits.
The stanch times at the different sides were recorded.
Then the rabbits were killed.
Pathological examination was made to the lung, liver, and kidney to observe the amount of small thrombus and inflammation.
CIE was performed at the right side of anus of 6 dogs and the right side was used as control side.
What Was Measured
The copper ion concentration was measured in 30 patients undergoing CIE.
PubMed files the paper under topics including Copper, Dogs, Electrochemistry, Gastrointestinal Hemorrhage, Hemorrhoids, Prolapse and Rabbits.
What This Means in Plain Language
This is a controlled clinical trial of Copper (Supplement) in 202 patients.
Results are reported in around 11 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2003 (Zhonghua yi xue za zhi), a journal based in China.
More context: the Copper (Supplement) compound page, all human trials.
Our Notes on the Compound
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.