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Evaluation of time required for recontamination of coronally sealed canals medicated with calcium hydroxide and chlorhexidine.

Plain-language guide to PMID 12950574 (2003): randomized controlled trial of Calcium Hydroxide and Chlorhexidine.

Key Facts

PMID
12950574
Journal
International endodontic journal
Year
2003
Study type
Randomized Controlled Trial
Authors
Gomes BP et al. (6 authors)
DOI
10.1046/j.1365-2591.2003.00694.x

What This Study Did, in Plain Language

What Was Tested

Researchers studied Calcium Hydroxide and Chlorhexidine in this randomized controlled trial publication.

Who Took Part

After biomechanical preparation of 75 teeth, they were randomly divided into nine groups according to the intracanal medicament and the coronal seal with 'Intermediate Restorative Material' (IRM) as follows: (i) 10 teeth medicated with CG, coronally unsealed; (ii) 10 teeth medicated with CaOH2, coronally unsealed; (iii) 10 teeth medicated with CaOH2 + CG, coronally unsealed; (iv) 10 teeth medicated with CG + coronal seal; (v) 10 teeth medicated with CaOH2 + coronal seal; (vi) 10 teeth medicated with CG + CaOH2 + coronal seal; (vii) 10 teeth without intracanal medicament and coronally sealed; (viii) 5 teeth without intracanal medicament and coronally unsealed, used as the positive control group (PC); (ix) 5 teeth with intact crowns used as the negative control group (NC).

How the Study Was Run

The design is described as randomized.

Because people in this Calcium Hydroxide study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Eighty intact, caries-free, premolar teeth with straight roots and mature apices were selected for the study.

Glass flasks were filled with Brain Heart Infusion broth (BHI), so that only the root apex was in contact with the broth, while the crown was immersed in human saliva + BHI (3:1).

What Was Measured

PubMed files the paper under topics including Anti-Infective Agents, Local, Calcium Hydroxide, Chlorhexidine, Dental Leakage, Dental Pulp Cavity, Methylmethacrylates and Root Canal Irrigants.

What This Means in Plain Language

The paper is a randomized study of Calcium Hydroxide and Chlorhexidine.

The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2003 (International endodontic journal), a journal based in England.

More context: all human trials.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.