Smoking cessation treatment among dually diagnosed individuals: preliminary evaluation of different pharmacotherapies.

What Was Tested

This clinical trial looks at Nicotine and Bupropion.

This descriptive, observational pilot study evaluated a smoking cessation intervention using open-label bupropion and nicotine replacement within an addiction treatment center for patients with high rates of comorbid psychiatric diagnoses.

Participants were 115 veterans receiving substance abuse treatment at a Veterans Administration outpatient program who voluntarily sought smoking cessation treatment.

Who Took Part

The study group was 47 participants.

The age groups tagged for this paper are adults and middle-aged adults, both men and women.

How the Study Was Run

The design is described as open-label and pilot.

Everyone knew when Nicotine was being given (open label), which is simpler to run but leaves more room for expectations to affect what is reported.

It is described as a pilot, a small early test of whether a larger Nicotine study would be practical.

What Was Measured

This descriptive, observational pilot study evaluated a smoking cessation intervention using open-label bupropion and nicotine replacement within an addiction treatment center for patients with high rates of comorbid psychiatric diagnoses.

Topics PubMed links to this paper include Bupropion, Counseling, Diagnosis, Dual (Psychiatry), Dopamine Uptake Inhibitors, Ganglionic Stimulants, Mental Disorders and Nicotine.

What This Means in Plain Language

The paper is an open-label and pilot study of Nicotine and Bupropion in 47 participants.

The publication is from 2003 (Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco), a journal based in England.

More context: the related Therapeutic nicotine (patch, non-peptide) library page, all human trials.