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The spontaneous LH surge in ovarian hyperstimulation for assisted reproductive technology.
Plain-language guide to PMID 1309115 (1992): randomized controlled trial of Chorionic Gonadotropin.
Key Facts
- PMID
- 1309115
- Journal
- Annals of the Academy of Medicine, Singapore
- Year
- 1992
- Study type
- Randomized Controlled Trial
- Authors
- Hoshiai H et al. (4 authors)
What This Study Did, in Plain Language
What Was Tested
Researchers studied Chorionic Gonadotropin in this randomized controlled trial publication.
Thirty-seven patients who underwent assisted reproductive technology programme, in vitro fertilisation or embryo transfer and gamete intra-fallopian transfer, were randomised into two groups in order to evaluate frequency of premature spontaneous LH surge when stimulated with different type of hMG.
Why It Was Studied
An hMG (FSH:LH = 1:1) was administered for eighteen patients (group A) and the different highly purified hMG (FSH:LH = 19:1) was administered for nineteen patients (group B).
Blood samples are drawn from day 3 of the cycle until hCG administration, and serum LH level are measured in the frozen samples.
Who Took Part
PubMed tags the participants as women only.
How the Study Was Run
In design terms this was a randomized study.
The participants were allocated by chance, so the Chorionic Gonadotropin group and the comparison group should start out alike.
What Was Measured
Blood samples are drawn from day 3 of the cycle until hCG administration, and serum LH level are measured in the frozen samples.
Topics PubMed links to this paper include Chorionic Gonadotropin, Embryo Transfer, Fertilization in Vitro, Follicle Stimulating Hormone, Gamete Intrafallopian Transfer, Luteinizing Hormone and Menotropins.
What This Means in Plain Language
The paper is a randomized study of Chorionic Gonadotropin.
The publication is from 1992 (Annals of the Academy of Medicine, Singapore), a journal based in Singapore.
More context: the related hCG (human chorionic gonadotropin) library page, all human trials.
Related Library Page
hCG (human chorionic gonadotropin): An LH analog that drives Leydig-cell testosterone production.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.