← Human Trials & Peer-Reviewed Studies

Oral magnesium and vitamin C supplements in asthma: a parallel group randomized placebo-controlled trial.

Plain-language guide to PMID 14519140 (2003): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
14519140
Journal
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Year
2003
Study type
Randomized Controlled Trial
Authors
Fogarty A et al. (7 authors)
DOI
10.1046/j.1365-2222.2003.01777.x

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

Who Took Part

The age groups tagged for this paper are teenagers, adults and middle-aged adults, both men and women.

How the Study Was Run

The researchers set it up as a randomized, double-blind, placebo-controlled and parallel-group study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.

The Vitamin D, K2, Magnesium and Zinc group and the comparison group ran side by side rather than switching.

The main outcome measures were change in forced expiratory volume in 1 s, forced vital capacity, airway responsiveness to methacholine, mean morning and evening peak flow, symptom scores and bronchodilator use, both individually and as a combined summary statistic.

What Was Measured

PubMed files the paper under topics including Ascorbic Acid, Asthma, Magnesium, Primary Health Care, Respiratory Mechanics and Treatment Refusal.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 2 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2003 (Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.