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Efficacy of zinc supplementation on the severity and duration of diarrhea in malnourished Turkish children.

Plain-language guide to PMID 14521531 (2003): double-blind controlled clinical trial of Vitamin D, K2, Magnesium and Zinc in 40 subjects.

Key Facts

PMID
14521531
Journal
Pediatrics international : official journal of the Japan Pediatric Society
Year
2003
Study type
Controlled Clinical Trial
Authors
Polat TB et al. (3 authors)
DOI
10.1046/j.1442-200x.2003.01772.x

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this controlled clinical trial publication.

A double-blind placebo-controlled study was designed to evaluate the effects of zinc supplementation on the clinical course and duration of diarrhea in malnourished Turkish children.

Who Took Part

The abstract describes 40 subjects taking part.

PubMed indexes the participants as infants and young children, both men and women.

The study group comprised 40 subjects with low zinc levels (Group 1a) and 52 subjects with normal zinc levels (Group 1b).

The control group was also comprised of two subgroups: 36 subjects with low zinc levels (Group 2a) and 54 subject with normal zinc levels (Group 2b).

How the Study Was Run

The design is described as double-blind and placebo-controlled.

Neither the subjects nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

Some subjects received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

What Was Measured

PubMed files the paper under topics including Case-Control Studies, Diarrhea, Infant Nutrition Disorders, Turkey and Zinc.

What This Means in Plain Language

The paper is a double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 40 subjects.

Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2003 (Pediatrics international : official journal of the Japan Pediatric Society), a journal based in Australia.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.