Additive effects of cortisol and growth hormone on regional and systemic lipolysis in humans.

What Was Tested

This randomized controlled trial looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Growth hormone (GH) and cortisol are important to ensure energy supplies during fasting and stress.

In vitro experiments have raised the question whether GH and cortisol mutually potentiate lipolysis.

Who Took Part

PubMed indexes the participants as adults, men only.

How the Study Was Run

The researchers set it up as a randomized, single-blind and placebo-controlled study.

The participants were allocated by chance, so the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group and the comparison group should start out alike.

Only one side, usually the participants, was kept unaware of whether Exogenous HGH, sermorelin & older GHRPs (why they're passed over) was given.

The comparison arm used a placebo, so changes seen with Exogenous HGH, sermorelin & older GHRPs (why they're passed over) could be set against what happens without it.

What Was Measured

A pancreatic-pituitary clamp was maintained with somatostatin infusion and replacement of GH, insulin, and glucagon at baseline levels.

Circulating levels of glucose, insulin, and glucagon were comparable in I-IV.

Topics PubMed links to this paper include Abdomen, Adipose Tissue, Drug Synergism, Fatty Acids, Nonesterified, Glycerol, Growth Hormone and Hydrocortisone.

What This Means in Plain Language

The paper is a randomized, single-blind and placebo-controlled study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

The publication is from 2004 (American journal of physiology. Endocrinology and metabolism), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.