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Quick parathormone assay in the surgical management of hyperparathyroidism

Plain-language guide to PMID 14650100 (2003): clinical trial study of Parathyroid Hormone (PTH 1-84) in 32 patients, hyperparathyroidism.

Key Facts

PMID
14650100
Journal
The Israel Medical Association journal : IMAJ
Year
2003
Study type
Clinical Trial
Authors
Halevy A et al. (12 authors)

What This Study Did, in Plain Language

What Was Tested

Researchers studied Parathyroid Hormone (PTH 1-84) in the context of hyperparathyroidism in this clinical trial publication.

To evaluate the contribution of QPTH measurements during parathyroidectomy to the achievement of higher success rates.

Why It Was Studied

Among the various new technologies in the field of parathyroid surgery is intraoperative quick parathormone measurements.

Who Took Part

According to the abstract, 32 patients were involved.

The age groups tagged for this paper are adults, middle-aged adults, older adults and people over 80, both men and women.

QPTH assay using Immulite Turbo Intact PTH was measured in 32 patients undergoing parathyroidectomy: 30 for primary and 2 for secondary hyperparathyroidism.

How the Study Was Run

QPTH levels were measured at time 0 minutes (before incision) and at 10, 20, and 30 minutes after excision of the hyperfunctioning gland.

What Was Measured

Among the various new technologies in the field of parathyroid surgery is intraoperative quick parathormone measurements.

Topics PubMed links to this paper include Adenoma, Choristoma, Hyperparathyroidism, Hyperplasia, Intraoperative Care, Neck and Outcome and Process Assessment, Health Care.

What This Means in Plain Language

This is a clinical trial of Parathyroid Hormone (PTH 1-84) in 32 patients in people with hyperparathyroidism.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2003 (The Israel Medical Association journal : IMAJ), a journal based in Israel.

More context: the Parathyroid Hormone (PTH 1-84) compound page, Hyperparathyroidism research.

Our Notes on the Compound

Parathyroid Hormone (PTH 1-84): The 84-amino-acid hormone that raises blood calcium; full-length PTH (Natpara) has been used in hypoparathyroidism. Teriparatide is its 1-34 fragment.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.