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Exercise training benefits growth hormone (GH)-deficient adults in the absence or presence of GH treatment.

Plain-language guide to PMID 14671161 (2003): double-blind randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Key Facts

PMID
14671161
Journal
The Journal of clinical endocrinology and metabolism
Year
2003
Study type
Randomized Controlled Trial
Authors
Thomas SG et al. (3 authors)
DOI
10.1210/jc.2003-030632

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Serum IGF-I levels were monitored to assess compliance with GH treatment.

Why It Was Studied

The researchers examined the effect of aerobic training on cycle ergometers in a double-blind crossover trial.

Who Took Part

The age groups tagged for this paper are adults, middle-aged adults and older adults.

How the Study Was Run

The design is described as randomized, double-blind, placebo-controlled and crossover.

Random assignment meant chance, not the researchers, decided who got Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and who got the comparison, which limits bias.

As a double-blind Exogenous HGH, sermorelin & older GHRPs (why they're passed over) study, the assignments were hidden from both participants and investigators until the end.

A placebo (an inactive look-alike) gave the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group a baseline to be compared against.

In the crossover set-up each of the participants took both Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and the comparison in turn, acting as their own control.

Peak oxygen uptake (VO(2)peak) and ventilation threshold (VeT) were measured during a progressive cycle ergometer test to fatigue or symptom-limited maximum.

What Was Measured

PubMed files the paper under topics including Affect, Exercise, Exercise Test, Human Growth Hormone, Insulin-Like Growth Factor I, Oxygen Consumption and Physical Education and Training.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

The publication is from 2003 (The Journal of clinical endocrinology and metabolism), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.