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Effects of vitamin D supplementation on strength, physical function, and health perception in older, community-dwelling men.
Plain-language guide to PMID 14687355 (2003): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 14687355
- Journal
- Journal of the American Geriatrics Society
- Year
- 2003
- Study type
- Randomized Controlled Trial
- Authors
- Kenny AM et al. (5 authors)
- DOI
- 10.1046/j.1532-5415.2003.51561.x
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.
To study the effects of vitamin D supplementation in healthier populations of men.
Who Took Part
The age groups tagged for this paper are older adults and people over 80, men only.
Sixty-five healthy, community-dwelling men (mean age+/-standard deviation=76+/-4, range 65-87).
Upper and lower extremity muscle strength and power, physical performance and activity, health perception, calcium and vitamin D intake, and biochemical assessment, including 25-hydroxyvitamin D (25OHD), parathyroid hormone (PTH), and ionized calcium levels.
How the Study Was Run
The design is described as randomized, double-blind and placebo-controlled.
Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
Neither the participants nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.
The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.
What Was Measured
Topics PubMed links to this paper include 25-Hydroxyvitamin D 2, Biomarkers, Health Status, Physical Fitness and Vitamin D.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.
The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2003 (Journal of the American Geriatrics Society), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.