Chemical ablation of endometrium with trichloroacetic acid

What Was Tested

The paper reports a study of Goserelin in the context of endometriosis, published as a controlled clinical trial.

This trial has also compared the advantages of prethinning the endometrium with danazol and goserelin acetate before ablation with TCA.

Who Took Part

According to the abstract, 30 patients were involved.

The age groups tagged for this paper are adults and middle-aged adults, women only.

This prospective trial was conducted on 90 volunteer cases.

Patients were allocated into three treatment groups comprised of 30 patients.

How the Study Was Run

In group II cases were administered danazol before ablation.

Cases in group III received goserelin acetate on the same day and 28 days after ablation.

Endometrium was evaluated by biopsy, transvaginal ultrasonography and hysteroscopy.

All of the patients were evaluated 3 and 6 months after TCA application.

What Was Measured

Topics PubMed links to this paper include Caustics, Danazol, Dilatation and Curettage, Endometrium, Estrogen Antagonists, Goserelin and Trichloroacetic Acid.

What This Means in Plain Language

This is a controlled clinical trial of Goserelin in 30 patients in people with endometriosis.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2004 (International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics), a journal based in United States.

More context: the Goserelin compound page, Endometriosis research.