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Effect of a micronutrient fortificant mixture and 2 amounts of calcium on iron and zinc absorption from a processed food supplement.
Plain-language guide to PMID 14749230 (2004): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).
Key Facts
- PMID
- 14749230
- Journal
- The American journal of clinical nutrition
- Year
- 2004
- Study type
- Randomized Controlled Trial
- Authors
- Mendoza C et al. (4 authors)
- DOI
- 10.1093/ajcn/79.2.244
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement), published as a randomized controlled trial.
The researchers evaluated the effect of a novel fortificant mixture consisting of NaFeEDTA, zinc methionine, ascorbic acid, and citric acid on iron and zinc absorption from a dry food supplement designed for preschool children.
Why It Was Studied
Iron, zinc, and calcium can interact with each other in a way that inhibits their respective absorption.
Who Took Part
By PubMed's age tags, the people studied were adults, women only.
The standard food supplement contained cereal and legume flour, dried milk, and a mixture of micronutrients including ferrous sulfate and zinc sulfate as sources of supplemental iron and zinc, respectively.
Iron absorption and zinc absorption from the food products were evaluated simultaneously in 13 nonpregnant, adult women by extrinsically labeling the products with radioisotopes of iron and zinc and carrying out whole-body counting 7 d after the food products were consumed in random order.
How the Study Was Run
The researchers set it up as a randomized study.
Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
What Was Measured
The subject headings attached to it are Calcium, Dietary Supplements, Edetic Acid, Ferric Compounds, Intestinal Absorption, Iron and Iron Chelating Agents.
What This Means in Plain Language
The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).
Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2004 (The American journal of clinical nutrition), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Copper (Supplement) compound page, all human trials.
Our Notes on the Compounds
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.