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Effect of growth hormone replacement therapy on pituitary hormone secretion and hormone replacement therapies in GHD adults.

Plain-language guide to PMID 14752209 (2004): double-blind randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 22 patients.

Key Facts

PMID
14752209
Journal
Hormone research
Year
2004
Study type
Randomized Controlled Trial
Authors
Hubina E et al. (7 authors)
DOI
10.1159/000076538

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), published as a randomized controlled trial.

Who Took Part

The study group was 22 patients.

The age groups tagged for this paper are adults, middle-aged adults and older adults, both men and women.

22 GHD patients were investigated in a double-blind randomized study and 90 GHD patients in an open study at baseline and after 6 and 12 months of GH replacement therapy.

How the Study Was Run

In design terms this was a randomized and double-blind study.

The patients were allocated by chance, so the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group and the comparison group should start out alike.

Blinding on both sides kept the patients and researchers unaware of who received Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

What Was Measured

The subject headings attached to it are Gonads, Growth Hormone, Hormone Replacement Therapy, Hormones, Human Growth Hormone, Insulin-Like Growth Factor I and Pituitary Gland.

What This Means in Plain Language

The paper is a randomized and double-blind study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 22 patients.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Results are reported in around 10 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2004 (Hormone research), a journal based in Switzerland.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.