← Human Trials & Peer-Reviewed Studies
Acute exposure to moderate high altitude decreases growth hormone response to physical exercise in untrained subjects.
Plain-language guide to PMID 14767420 (2003): randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).
Key Facts
- PMID
- 14767420
- Journal
- The Journal of sports medicine and physical fitness
- Year
- 2003
- Study type
- Randomized Controlled Trial
- Authors
- Gutiérrez A et al. (5 authors)
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over).
Physical exercise in recreational mountain sports is frequently performed without acclimatization to hypoxic conditions.
Hypoxia may modify the hormonal and metabolic adaptive response to exercise depending on the type of exercise and on the physical fitness of the subject.
This study aims at investigating the growth hormone (GH) response to submaximal exercise after acute exposure to moderate high altitude.
Who Took Part
PubMed indexes the participants as adults, men only.
Ten trained (T) and 10 untrained (UT) male volunteers (mean age 23.8+/-3.2 y) underwent, in random order, 2 submaximal exercise (ergocycle) tests of the same absolute intensity.
How the Study Was Run
The researchers set it up as a randomized study.
Because people in this Exogenous HGH, sermorelin & older GHRPs (why they're passed over) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
One test was performed at their habitual living altitude (690 m above sea level); the other, after acute exposure to 2325 m above sea level.
Plasma levels of GH, Insulin-like growth factor-1 (IGF-1) and lactate were measured before and immediately after the exercise tests.
What Was Measured
The subject headings attached to it are Altitude, Exercise Test, Growth Hormone, Hypoxia, Insulin-Like Growth Factor I, Lactic Acid and Physical Fitness.
What This Means in Plain Language
The paper is a randomized study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).
Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2003 (The Journal of sports medicine and physical fitness), a journal based in Italy.
More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.
Our Notes on the Compound
Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.