← Human Trials & Peer-Reviewed Studies
Vitamin D and calcium supplementation prevents osteoporotic fractures in elderly community dwelling residents: a pragmatic population-based 3-year intervention study.
Plain-language guide to PMID 15040824 (2004): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 4957 participants.
Key Facts
- PMID
- 15040824
- Journal
- Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
- Year
- 2004
- Study type
- Randomized Controlled Trial
- Authors
- Larsen ER et al. (3 authors)
- DOI
- 10.1359/JBMR.0301240
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.
Who Took Part
The abstract describes 4957 participants taking part.
The age groups tagged for this paper are older adults, both men and women.
How the Study Was Run
The researchers set it up as a randomized study.
Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.
This was a factorial, cluster-randomized, pragmatic, intervention study.
The researchers included 9605 community-dwelling residents aged 66+ years.
The researchers achieved information on osteoporotic fractures in the study population from the Danish Hospital Registration Database.
The researchers defined osteoporotic fractures as low energy fractures of the proximal humerus, distal forearm, vertebral column, pelvis, cervical femur, and intertrochanteric femur.
What Was Measured
The subject headings attached to it are Calcium, Dietary, Community Health Services, Denmark, Fractures, Bone, Hospitalization, Mortality and Osteoporosis.
What This Means in Plain Language
The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 4957 participants.
With several hundred people or more, it is a fairly large study for this kind of research.
Its findings take up roughly 3 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2004 (Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research), a journal based in England.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.