← Human Trials & Peer-Reviewed Studies

Manual removal or spontaneous placental delivery and postcesarean endometritis and bleeding

Plain-language guide to PMID 15207663 (2004): randomized controlled trial study of Oxytocin in 400 women, endometriosis.

Key Facts

PMID
15207663
Journal
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Year
2004
Study type
Randomized Controlled Trial
Authors
Dehbashi S et al. (3 authors)
DOI
10.1016/j.ijgo.2003.11.001

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Oxytocin in the context of endometriosis, published as a randomized controlled trial.

To compare the effect of manual removal and spontaneous delivery of placenta on postcesarean bleeding and endometritis.

Who Took Part

The study group was 400 women.

PubMed indexes the participants as adults, women only.

In this prospective study 400 pregnant women undergoing elective cesarean delivery were randomly assigned to two groups: spontaneous placental delivery (200 women) and manual placental delivery (200).

Endometritis was diagnosed in patients who developed clinical signs of fever and suprapubic tenderness 48 h after delivery.

How the Study Was Run

In design terms this was a randomized study.

The women were allocated by chance, so the Oxytocin group and the comparison group should start out alike.

No antibiotic prophylaxis was administered in either group.

The researchers analyzed the data using a t-test.

What Was Measured

The subject headings attached to it are Cesarean Section, Endometritis, Hemoglobins, Incidence, Labor Stage, Third, Oxytocics and Oxytocin.

What This Means in Plain Language

The paper is a randomized study of Oxytocin in 400 women in people with endometriosis.

With several hundred people or more, it is a fairly large study for this kind of research.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2004 (International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics), a journal based in United States.

More context: the Oxytocin compound page, Endometriosis research.

Our Notes on the Compound

Oxytocin: A peptide hormone with established obstetric medical uses and a less settled role in research on behavior, sexual function and appetite.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.