Magnesium in addition to sotalol does not influence the incidence of postoperative atrial tachyarrhythmias after coronary artery bypass surgery.

What Was Tested

The paper reports a study of Sotalol and Magnesium Chloride, published as a randomized controlled trial.

Several etiologic factors are mentioned.

Who Took Part

The abstract describes 74 patients taking part.

PubMed indexes the participants as middle-aged adults, both men and women.

After institutional approval and written informed consent, patients undergoing CABG with use of cardiopulmonary bypass were included in a prospective, randomized, placebo-controlled double-blind study.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

Because people in this Sotalol study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Blinding on both sides kept the patients and researchers unaware of who received Sotalol.

Some patients received a placebo instead of Sotalol, giving a reference point.

Prospective, randomized, double-blinded, placebo-controlled trial.

In both groups, sotalol orally was started 16 to 24 hours after CABG.

The incidence and duration of in-hospital POAT were evaluated.

What Was Measured

PubMed files the paper under topics including Anti-Arrhythmia Agents, Atrial Fibrillation, Atrial Flutter, Cardiopulmonary Bypass, Coronary Artery Bypass, Heart Atria and Magnesium Chloride.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Sotalol and Magnesium Chloride in 74 patients.

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2004 (Journal of cardiothoracic and vascular anesthesia), a journal based in United States.

More context: all human trials.