Dual growth hormone (GH) response to repeated GH releasing hormone stimulus in children and adults.

What Was Tested

This clinical trial looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and GHRH (Growth Hormone-Releasing Hormone).

The aim of the present study was to evaluate the dual GH response to repeated GHRH stimuli to clarify the possible influence of somatostatinergic activity in the type of response.

Why It Was Studied

An additional group of 10 normal adults with similar characteristics (mean age 31 years, range 25-35 years) were also recruited as a control group for somatostatinergic assessment.

The GH response to the first GHRH bolus was similar in both children and adults.

Who Took Part

The study group was 19 volunteers.

By PubMed's age tags, the people studied were children, teenagers and adults.

What Was Measured

An additional group of 10 normal adults with similar characteristics (mean age 31 years, range 25-35 years) were also recruited as a control group for somatostatinergic assessment.

The subject headings attached to it are Age Factors, Down-Regulation, Drug Tolerance, Growth Hormone, Growth Hormone-Releasing Hormone, Stimulation, Chemical and Thyrotropin.

What This Means in Plain Language

This is a clinical trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and GHRH (Growth Hormone-Releasing Hormone) in 19 volunteers.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 2004 (Journal of pediatric endocrinology & metabolism : JPEM), a journal based in Germany.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page and the GHRH (Growth Hormone-Releasing Hormone) compound page, all human trials.