Dialysate magnesium level and blood pressure.

What Was Tested

This randomized controlled trial looks at Magnesium in the context of low blood pressure and orthostatic hypotension.

The researchers investigated the way dialysate magnesium (dMg) concentrations could affect blood pressure (BP) during hemodialysis (HD).

Who Took Part

The study group was 14 patients.

The age groups tagged for this paper are middle-aged adults and older adults, both men and women.

Eight HD patients underwent four midweek HD treatments consecutively, using, during each four-hour HD session, one of the following four dialysate formulations, in randomized order, which differed only with regard to dMg and dialysate calcium (dCa) concentrations (in mmol/L): 0.75 dMg, 1.75 dCa (group I); 0.25 dMg, 1.75 dCa (group II); 0.75 dMg, 1.25 dCa (group III); 0.25 dMg, 1.25 dCa (group IV).

How the Study Was Run

The design is described as randomized.

Because people in this Magnesium study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

BP and symptoms were recorded during each HD session.

What Was Measured

PubMed files the paper under topics including Blood Pressure, Calcium, Hemodialysis Solutions, Hypotension, Kidney Failure, Chronic, Magnesium and Myocardial Contraction.

What This Means in Plain Language

The paper is a randomized study of Magnesium in 14 patients in people with low blood pressure and orthostatic hypotension.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2004 (Kidney international), a journal based in United States.

More context: the related Vitamin D, K2, Magnesium and Zinc library page, Low blood pressure and orthostatic hypotension research.