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Iron and zinc supplementation promote motor development and exploratory behavior among Bangladeshi infants.
Plain-language guide to PMID 15447897 (2004): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 221 infants.
Key Facts
- PMID
- 15447897
- Journal
- The American journal of clinical nutrition
- Year
- 2004
- Study type
- Randomized Controlled Trial
- Authors
- Black MM et al. (10 authors)
- DOI
- 10.1093/ajcn/80.4.903
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.
Multivariate analyses were conducted to examine the change in development and behavior for each supplementation group, with control for maternal education, HOME score, months breastfed, anemia, growth at 6 mo, and change in growth from 6 to 12 mo.
Why It Was Studied
Iron and zinc deficiency are prevalent during infancy in low-income countries.
Who Took Part
According to the abstract, 221 infants were involved.
By PubMed's age tags, the people studied were infants, both men and women.
The participants were 221 infants from rural Bangladesh at risk of micronutrient deficiencies.
Development and behavior were evaluated at 6 and 12 mo of age by using the Bayley Scales of Infant Development II and the Home Observation Measurement of Environment (HOME) scale.
How the Study Was Run
The design is described as randomized and double-blind.
Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.
What Was Measured
Topics PubMed links to this paper include Anemia, Iron-Deficiency, Bangladesh, Child Development, Dietary Supplements, Drug Combinations, Drug Synergism and Exploratory Behavior.
What This Means in Plain Language
The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 221 infants.
Results are reported in around 4 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2004 (The American journal of clinical nutrition), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.