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The influence of some antipsychotics on erythrocyte magnesium and plasma magnesium, calcium, copper and zinc in patients with paranoid schizophrenia.
Plain-language guide to PMID 15466963 (2004): randomized controlled trial of Antipsychotic Agents in 56 patients.
Key Facts
- PMID
- 15466963
- Journal
- Journal of the American College of Nutrition
- Year
- 2004
- Study type
- Randomized Controlled Trial
- Authors
- Nechifor M et al. (5 authors)
- DOI
- 10.1080/07315724.2004.10719401
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Antipsychotic Agents, published as a randomized controlled trial.
The aim of the study was the investigation of plasma magnesium, calcium, copper and zinc and erythrocyte magnesium levels in patients with paranoid schizophrenia and the influence of the therapy with two antipsychotic drugs (haloperidol and risperidone) on these concentrations.
Who Took Part
The study group was 56 patients.
By PubMed's age tags, the people studied were teenagers, adults, middle-aged adults and older adults, both men and women.
The researchers investigated the influence of treatment with haloperidol and risperidoneon plasma and erythrocyte magnesium and on plasmatic levels of zinc, calcium and copper on hospitalized 56 patients diagnosed with paranoid schizophrenia (DSM IV).
How the Study Was Run
The researchers set it up as a randomized study.
Because people in this Antipsychotic Agents study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
What Was Measured
Topics PubMed links to this paper include Antipsychotic Agents, Biomarkers, Calcium, Copper, Erythrocytes, Haloperidol and Magnesium.
What This Means in Plain Language
The paper is a randomized study of Antipsychotic Agents in 56 patients.
Its findings take up roughly 3 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2004 (Journal of the American College of Nutrition), a journal based in United States.
More context: all human trials.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.