← Human Trials & Peer-Reviewed Studies
The second progress report on the Hypertension Objective treatment based on Measurement by Electrical Devices of Blood Pressure (HOMED-BP) study.
Plain-language guide to PMID 15472496 (2004): randomized controlled trial of Angiotensin II Type 1 Receptor Blockers, low blood pressure and orthostatic hypotension.
Key Facts
- PMID
- 15472496
- Journal
- Blood pressure monitoring
- Year
- 2004
- Study type
- Randomized Controlled Trial
- Authors
- Saito S et al. (10 authors)
- DOI
- 10.1097/00126097-200410000-00003
What This Study Did, in Plain Language
What Was Tested
Researchers studied Angiotensin II Type 1 Receptor Blockers in the context of low blood pressure and orthostatic hypotension in this randomized controlled trial publication.
The Hypertension Objective treatment based on Measurement by Electrical Devices of Blood Pressure (HOMED-BP) study is a large-scale intervention trial to determine both optimal target blood pressure (BP) on the basis of self-measured BP at home, and optimal initial antihypertensive medication.
To investigate the quality of randomization at the end of March 2003, and BP-controlled conditions during initial 6 months.
Who Took Part
The researchers evaluated the number of patients randomized by the end of March 2003, and BP changes during the initial 6 months based on intention-to-treat analysis.
How the Study Was Run
In design terms this was a randomized study.
Because people in this Angiotensin II Type 1 Receptor Blockers study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
What Was Measured
The subject headings attached to it are Angiotensin II Type 1 Receptor Blockers, Angiotensin-Converting Enzyme Inhibitors, Blood Pressure, Blood Pressure Determination, Calcium Channel Blockers, Clinical Protocols and Hypertension.
What This Means in Plain Language
The paper is a randomized study of Angiotensin II Type 1 Receptor Blockers in people with low blood pressure and orthostatic hypotension.
Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2004 (Blood pressure monitoring), a journal based in England.
More context: Low blood pressure and orthostatic hypotension research.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.