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Telmisartan in the treatment of hypertension in patients with chronic renal insufficiency.
Plain-language guide to PMID 15523550 (2004): clinical trial of Angiotensin-Converting Enzyme Inhibitors in 10 patients.
Key Facts
- PMID
- 15523550
- Journal
- Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia
- Year
- 2004
- Study type
- Clinical Trial
- Authors
- Weinbergová O et al. (5 authors)
What This Study Did, in Plain Language
What Was Tested
Researchers studied Angiotensin-Converting Enzyme Inhibitors in this clinical trial publication.
Its effect on proteinuria, renal function (represented by serum urea, creatinine, glomerular filtration), evaluation of overall therapy compliance in comparison with a previously prescribed angiotensin converting enzyme inhibitors (ACEI) were secondary aims.
Considering the presence of left ventricle hypertrophy in all patients as a marker of hypertensive cardiopathy, the effect of telmisartan therapy on non-invasive cardiovascular parameters (ECG, echocardiography, and assessment of heart rate variability-HRV) was also evaluated.
Who Took Part
The abstract describes 10 patients taking part.
PubMed tags the participants as both men and women.
What Was Measured
Its effect on proteinuria, renal function (represented by serum urea, creatinine, glomerular filtration), evaluation of overall therapy compliance in comparison with a previously prescribed angiotensin converting enzyme inhibitors (ACEI) were secondary aims.
Considering the presence of left ventricle hypertrophy in all patients as a marker of hypertensive cardiopathy, the effect of telmisartan therapy on non-invasive cardiovascular parameters (ECG, echocardiography, and assessment of heart rate variability-HRV) was also evaluated.
PubMed files the paper under topics including Angiotensin II Type 1 Receptor Blockers, Angiotensin-Converting Enzyme Inhibitors, Benzimidazoles, Benzoates, Blood Pressure, Diabetic Nephropathies and Heart Rate.
What This Means in Plain Language
This is a clinical trial of Angiotensin-Converting Enzyme Inhibitors in 10 patients.
With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.
The publication is from 2004 (Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia), a journal based in Czech Republic.
More context: all human trials.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.