Interaction of fat availability and sex on postprandial satiety and cholecystokinin after mixed-food meals

What Was Tested

The paper reports a study of Cholecystokinin (CCK), published as a randomized controlled trial.

The primary objective of the present study was to determine, in an acute meal setting, whether the availability of dietary fat for alimentary processing, and hence the stimulation of CCK, affects the postmeal satiety response in men and women.

Visual analogue scales were used to assess indexes of satiety at defined time points up to 6 h after meal consumption.

Who Took Part

The abstract describes 8 men taking part.

The age groups tagged for this paper are adults, both men and women.

In a within-subjects design, subjects (8 men, 7 women) consumed 1 of 3 isoenergetic mixed-food test meals 1 wk apart in random order.

Blood was sampled at corresponding time points for measurement of CCK, glucose, insulin, and triacylglycerol.

How the Study Was Run

The researchers set it up as a randomized study.

Random assignment meant chance, not the researchers, decided who got Cholecystokinin (CCK) and who got the comparison, which limits bias.

Subsequent food intake was also assessed.

What Was Measured

Topics PubMed links to this paper include Biological Availability, Cholecystokinin, Diet, Dietary Fats, Pain Measurement, Plant Oils and Prunus.

What This Means in Plain Language

The paper is a randomized study of Cholecystokinin (CCK) in 8 men.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2004 (The American journal of clinical nutrition), a journal based in United States.

More context: the Cholecystokinin (CCK) compound page, all human trials.