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[Clearance effect of different blood purification techniques on parathyroid hormone in renal function failure patients on maintenance hemodialysis]

Plain-language guide to PMID 15585154 (2004): randomized controlled trial of Parathyroid Hormone (PTH 1-84).

Key Facts

PMID
15585154
Journal
Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
Year
2004
Study type
Randomized Controlled Trial
Authors
Wang C et al. (6 authors)

What This Study Did, in Plain Language

What Was Tested

Researchers studied Parathyroid Hormone (PTH 1-84) in this randomized controlled trial publication.

To evaluate the effect of different blood purification techniques on serum parathyroid hormone (PTH) level in chronic hemodialysis (HD) patients with renal failure.

Who Took Part

The age groups tagged for this paper are adults, middle-aged adults and older adults, both men and women.

Ninety patients were randomly divided into three groups: absorption (AP) group, hemodiafiltration (HDF) group, and HD group.

Blood routine examination, serum albumin, globulin, blood urea nitrogen, creatinine and PTH were measured before and after these treatments, and vital signs and side effects were recorded during HD.

How the Study Was Run

The design is described as randomized.

Random assignment meant chance, not the researchers, decided who got Parathyroid Hormone (PTH 1-84) and who got the comparison, which limits bias.

Glomerular filtration rate (GFR) and the length of HD were compared among three group.

What Was Measured

The subject headings attached to it are Hemofiltration, Kidney Failure, Chronic, Parathyroid Hormone, Renal Dialysis and Sorption Detoxification.

What This Means in Plain Language

The paper is a randomized study of Parathyroid Hormone (PTH 1-84).

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2004 (Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue), a journal based in China.

More context: the Parathyroid Hormone (PTH 1-84) compound page, all human trials.

Our Notes on the Compound

Parathyroid Hormone (PTH 1-84): The 84-amino-acid hormone that raises blood calcium; full-length PTH (Natpara) has been used in hypoparathyroidism. Teriparatide is its 1-34 fragment.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.