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Trial of zinc supplements in relation to pregnancy outcomes, hematologic indicators, and T cell counts among HIV-1-infected women in Tanzania.

Plain-language guide to PMID 15640476 (2005): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
15640476
Journal
The American journal of clinical nutrition
Year
2005
Study type
Randomized Controlled Trial
Authors
Fawzi WW et al. (7 authors)
DOI
10.1093/ajcn/81.1.161

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

The researchers examined the effects of zinc supplements on birth outcomes, hematologic indicators, and counts of T lymphocyte subsets among 400 HIV-infected pregnant women.

Why It Was Studied

Such endpoints may affect the risk of adverse birth outcomes among HIV-infected women.

Who Took Part

PubMed indexes the participants as adults, women only.

All women received iron, folic acid, and multivitamin supplements irrespective of the experimental assignment.

How the Study Was Run

The researchers set it up as a randomized and placebo-controlled study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

What Was Measured

Such endpoints may affect the risk of adverse birth outcomes among HIV-infected women.

PubMed files the paper under topics including Birth Weight, CD4-CD8 Ratio, HIV Infections, HIV-1, Pregnancy Outcome, Prenatal Care and T-Lymphocyte Subsets.

What This Means in Plain Language

The paper is a randomized and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2005 (The American journal of clinical nutrition), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.