← Human Trials & Peer-Reviewed Studies
In vivo antimicrobial effectiveness of an essential oil-containing mouth rinse 12 h after a single use and 14 days' use.
Plain-language guide to PMID 15811048 (2005): double-blind randomized controlled trial of Anti-Infective Agents, Local.
Key Facts
- PMID
- 15811048
- Journal
- Journal of clinical periodontology
- Year
- 2005
- Study type
- Randomized Controlled Trial
- Authors
- Fine DH et al. (6 authors)
- DOI
- 10.1111/j.1600-051x.2005.00674.x
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Anti-Infective Agents, Local.
Who Took Part
By PubMed's age tags, the people studied were adults and middle-aged adults, both men and women.
How the Study Was Run
In design terms this was a randomized, double-blind and crossover study.
The participants were allocated by chance, so the Anti-Infective Agents, Local group and the comparison group should start out alike.
Blinding on both sides kept the participants and researchers unaware of who received Anti-Infective Agents, Local.
Each person switched between Anti-Infective Agents, Local and the comparison at some point, usually with a gap in between.
These studies utilized a randomized, double-blind, controlled crossover design.
Bacterial sampling was repeated 12 h after the first rinse, and again 12 h after the final rinse 14 days later.
The sampling schedule was adjusted according to whether the study was investigating daytime or overnight activity.
Samples were plated on Schaedlers medium (total anaerobes), Schaedlers Nalidixic/Vancomycin medium (Gram-negative anaerobes), and OOPS medium (volatile sulphur compound (VSC)-producing organisms).
Inter-group log10 transformed colony-forming units/ml counts from samples of supragingival plaque and tongue swabs on each of the three media were compared by analysis of covariance.
What Was Measured
The subject headings attached to it are Anti-Infective Agents, Local, Bacteria, Bacteria, Anaerobic, Chlorides, Colony Count, Microbial, Dental Plaque and Halitosis.
What This Means in Plain Language
The paper is a randomized, double-blind and crossover study of Anti-Infective Agents, Local.
Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2005 (Journal of clinical periodontology), a journal based in United States.
More context: all human trials.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.