Polyphenol-rich phloem enhances the resistance of total serum lipids to oxidation in men.

What Was Tested

The paper reports a study of Copper, published as a randomized controlled trial.

Their aim was to investigate the effects of a 4-week consumption of polyphenol-rich phloem on serum lipids and lipid peroxidation in the hydrophilic fraction of serum and on isolated lipoproteins.

Why It Was Studied

The researchers conducted a randomized double-blind supplementation study consisting of 75 nonsmoking hypercholesterolemic men.

Who Took Part

According to the abstract, 75 men were involved.

The age groups tagged for this paper are adults, middle-aged adults and older adults, men only.

The ex vivo susceptibility of total serum lipids and VLDL and LDL to oxidation after copper induction was measured as a lag time to the maximal oxidation rate at the baseline and after the supplementation.

How the Study Was Run

In design terms this was a randomized, double-blind and placebo-controlled study.

Because people in this Copper study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

As a double-blind Copper study, the assignments were hidden from both participants and investigators until the end.

Some men received a placebo instead of Copper, giving a reference point.

What Was Measured

PubMed files the paper under topics including Bread, Copper, Flavonoids, Food, Fortified, Hypercholesterolemia, Lipid Peroxidation and Lipids.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Copper in 75 men.

The publication is from 2005 (Journal of agricultural and food chemistry), a journal based in United States.

More context: the related Copper (Supplement) library page, all human trials.