The influence of growth hormone therapy on ultrasound myocardial tissue characterization in patients with childhood onset GH deficiency.

What Was Tested

This clinical trial looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

In this study, the researchers investigated the effects of 12 months of GH replacement therapy on cardiac structure and functional indices measured by echocardiographic techniques in adult patients with childhood onset GH deficiency.

Who Took Part

By PubMed's age tags, the people studied were teenagers, adults and middle-aged adults, both men and women.

How the Study Was Run

Echocardiography was performed including the ultrasound myocardial tissue characterization technique.

The researchers measured two parameters of the ultrasonic tissue characterization with integrated backscatter: the magnitude of the cardiac-cycle-dependent variation in integrated backscatter signals (CV-IBS) and the mean value of integrated backscatter signals calibrated by the pericardium (cal-IBS).

What Was Measured

In this study, the researchers investigated the effects of 12 months of GH replacement therapy on cardiac structure and functional indices measured by echocardiographic techniques in adult patients with childhood onset GH deficiency.

Topics PubMed links to this paper include Echocardiography, Doppler, Heart, Hormone Replacement Therapy, Human Growth Hormone, Insulin-Like Growth Factor I, Myocardial Contraction and Recombinant Proteins.

What This Means in Plain Language

This is a clinical trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2005 (International journal of cardiology), a journal based in Netherlands.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.