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The effect of HMG and recombinant human FSH on oocyte quality: a randomized single-blind clinical trial.

Plain-language guide to PMID 15925050 (2005): single-blind randomized controlled trial of Follicle Stimulating Hormone.

Key Facts

PMID
15925050
Journal
European journal of obstetrics, gynecology, and reproductive biology
Year
2005
Study type
Randomized Controlled Trial
Authors
Rashidi BH et al. (6 authors)
DOI
10.1016/j.ejogrb.2004.11.007

What This Study Did, in Plain Language

What Was Tested

Researchers studied Follicle Stimulating Hormone in this randomized controlled trial publication.

To compare the effect of HMG and rhFSH on oocyte quality in ICSI cycle.

Why It Was Studied

Statistical analyses were carried out by the Mann-Whitney, Fisher's exact, chi2 tests and Student's t-test.

Who Took Part

By PubMed's age tags, the people studied were adults, women only.

Sixty women undergoing ovarian stimulation for ICSI were randomized to receive a standard protocol of either HMG or rhFSH in down-regulation cycles.

How the Study Was Run

The design is described as randomized and single-blind.

The participants were allocated by chance, so the Follicle Stimulating Hormone group and the comparison group should start out alike.

In this single-blind Follicle Stimulating Hormone study one party knew the assignments and the other did not.

Prospective single-blind randomized clinical trial.

Prior to microinjection, each oocyte was assessed regarding the nuclear maturity, morphology of zona plucida, cytoplasmic appearance and polar body morphology.

What Was Measured

Statistical analyses were carried out by the Mann-Whitney, Fisher's exact, chi2 tests and Student's t-test.

The subject headings attached to it are Embryo Implantation, Embryo Transfer, Follicle Stimulating Hormone, Menotropins, Microinjections, Oocytes and Ovulation Induction.

What This Means in Plain Language

The paper is a randomized and single-blind study of Follicle Stimulating Hormone.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2005 (European journal of obstetrics, gynecology, and reproductive biology), a journal based in Ireland.

More context: all human trials.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.