Postprandial acylated ghrelin status following fat and protein manipulation of meals in healthy young women

What Was Tested

The paper reports a study of Ghrelin, published as a randomized controlled trial.

The aim of the present study was to investigate the postprandial effect of diet composition on circulating acylated ghrelin levels in healthy women.

Why It Was Studied

A randomized cross-over study of three experimental treatments was performed.

A total of 11 healthy young women of normal body weight completed the study.

Who Took Part

According to the abstract, 11 women were involved.

The age groups tagged for this paper are adults, women only.

How the Study Was Run

The design is described as randomized and crossover.

Because people in this Ghrelin study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Each person switched between Ghrelin and the comparison at some point, usually with a gap in between.

What Was Measured

The test meals were administered 1 month apart.

Blood samples were withdrawn immediately before and at 15, 30, 60, 120 and 180 min after the test meal for measurement of plasma acylated ghrelin, as well as serum glucose, insulin and triacylglycerol (triglyceride) levels.

Topics PubMed links to this paper include Acylation, Blood Glucose, Blood Specimen Collection, Dietary Fats, Dietary Proteins, Fasting and Ghrelin.

What This Means in Plain Language

The paper is a randomized and crossover study of Ghrelin in 11 women.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 2005 (Clinical science (London, England : 1979)), a journal based in England.

More context: the Ghrelin compound page, all human trials.