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The effectiveness of calcitonin on chronic back pain and daily activities in postmenopausal women with osteoporosis

Plain-language guide to PMID 16193299 (2006): randomized controlled trial study of Calcitonin in 40 women, chronic pain: fibromyalgia & crps.

Key Facts

PMID
16193299
Journal
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Year
2006
Study type
Randomized Controlled Trial
Authors
Papadokostakis G et al. (5 authors)
DOI
10.1007/s00586-005-0916-4

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Calcitonin in the context of chronic pain: fibromyalgia & crps, published as a randomized controlled trial.

The aim of this study was to investigate the effect of nasal calcitonin on chronic back pain and disability attributed to osteoporosis.

Why It Was Studied

The study design involved three groups of osteoporotic postmenopausal women suffering from chronic back pain.

Group I consisted of 40 women with vertebral fractures, group II of 30 women with degenerative disorders and group III of 40 patients with non specific chronic back pain and without abnormality on plain X-rays.

Who Took Part

The abstract describes 40 women taking part.

PubMed tags the participants as women only.

How the Study Was Run

The researchers set it up as a randomized study.

The women were allocated by chance, so the Calcitonin group and the comparison group should start out alike.

Pain intensity was measured using a numerical rating scale (NRS) and disability due to back pain was measured using the Oswestry disability questionnaire.

What Was Measured

The subject headings attached to it are Activities of Daily Living, Back Pain, Calcitonin, Calcium, Chronic Disease, Osteoporosis, Postmenopausal and Pain Measurement.

What This Means in Plain Language

The paper is a randomized study of Calcitonin in 40 women in people with chronic pain: fibromyalgia & crps.

The publication is from 2006 (European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society), a journal based in Germany.

More context: the Calcitonin compound page, Chronic pain: fibromyalgia & CRPS research.

Our Notes on the Compound

Calcitonin: A 32-amino-acid hormone that lowers blood calcium; salmon calcitonin (Miacalcin) has been used for Paget disease and osteoporosis.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.