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Effects of calcium, dairy product, and vitamin D supplementation on bone mass accrual and body composition in 10-12-y-old girls: a 2-y randomized trial.
Plain-language guide to PMID 16280447 (2005): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 195 girls.
Key Facts
- PMID
- 16280447
- Journal
- The American journal of clinical nutrition
- Year
- 2005
- Study type
- Randomized Controlled Trial
- Authors
- Cheng S et al. (16 authors)
- DOI
- 10.1093/ajcn/82.5.1115
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.
The purpose was to examine the effects of both food-based and pill supplements of calcium and vitamin D on bone mass and body composition in girls aged 10-12 y.
Who Took Part
According to the abstract, 195 girls were involved.
The age groups tagged for this paper are children, women only.
How the Study Was Run
In design terms this was a randomized, double-blind and placebo-controlled study.
Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.
Blinding on both sides kept the girls and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.
Some girls received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.
Primary outcomes were bone indexes of the hip, spine, and whole body by dual-energy X-ray absorptiometry and of the radius and tibia by peripheral quantitative computed tomography.
What Was Measured
PubMed files the paper under topics including Absorptiometry, Photon, Analysis of Variance, Body Composition, Bone Density, Bone Density Conservation Agents, Bone Development and Bone Remodeling.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 195 girls.
The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2005 (The American journal of clinical nutrition), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.