Randomised clinical trial investigating the effects of combined administration of octreotide and methylglucamine diatrizoate in the older persons with adhesive small bowel obstruction

What Was Tested

Researchers studied Octreotide in this randomized controlled trial publication.

To investigate the effects of combined administration of octreotide and methylglucamine diatrizoate in the older persons with adhesive small bowel obstruction.

Who Took Part

The age groups tagged for this paper are older adults and people over 80, both men and women.

One hundred and sixty-two consecutive patients who had suffered from adhesive intestinal obstruction without clinical evidence of strangulation or gangrene were randomised into two groups, a control group (treated conservatively, n=82) and a contrast group (treated with combined administration of octreotide and methylglucamine diatrizoate, n=80).

How the Study Was Run

The researchers set it up as a randomized study.

The participants were allocated by chance, so the Octreotide group and the comparison group should start out alike.

A laparotomy was performed in both the two groups if symptoms of strangulation developed or the obstruction did not resolve spontaneously after 72 h.

What Was Measured

PubMed files the paper under topics including Contrast Media, Diatrizoate Meglumine, Gastrointestinal Agents, Intestinal Obstruction, Intestine, Small, Intubation, Gastrointestinal and Length of Stay.

What This Means in Plain Language

The paper is a randomized study of Octreotide.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2006 (Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver), a journal based in Netherlands.

More context: the Octreotide compound page, all human trials.