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Effect of vitamin D supplementation on vitamin D status and bone turnover markers in young adults.
Plain-language guide to PMID 16391584 (2006): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 15 subjects.
Key Facts
- PMID
- 16391584
- Journal
- European journal of clinical nutrition
- Year
- 2006
- Study type
- Randomized Controlled Trial
- Authors
- Barnes MS et al. (5 authors)
- DOI
- 10.1038/sj.ejcn.1602374
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.
To assess the vitamin D status of healthy young people living in Northern Ireland and the effect of vitamin D supplementation on vitamin D status and bone turnover.
Who Took Part
The study group was 15 subjects.
By PubMed's age tags, the people studied were teenagers and adults, both men and women.
In total, 30 apparently healthy students (15 male and 15 female subjects), aged 18-27 years, were recruited from the university, with 27 completing the intervention.
How the Study Was Run
In design terms this was a randomized and double-blind study.
The subjects were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.
Blinding on both sides kept the subjects and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.
Double-blinded randomised controlled intervention study.
University of Ulster, Coleraine, Northern Ireland.
Vitamin D status, bone turnover markers, serum calcium and parathyroid hormone concentrations were measured at baseline and post intervention.
What Was Measured
Topics PubMed links to this paper include Biomarkers, Bone Density Conservation Agents, Bone and Bones, Calcium, Dietary, Dietary Supplements, Health Status and Health Surveys.
What This Means in Plain Language
The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 15 subjects.
With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.
Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2006 (European journal of clinical nutrition), a journal based in England.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.