Energy intake, ghrelin, and cholecystokinin after different carbohydrate and protein preloads in overweight men

What Was Tested

The paper reports a study of Ghrelin and Cholecystokinin (CCK), published as a randomized controlled trial.

The objective of the study is to compare the acute effect of different proteins and carbohydrates on indicators of appetite and appetite regulatory hormones.

Why It Was Studied

Dietary proteins appear to be more satiating than carbohydrate.

The mechanism and effect of protein and carbohydrate type are unclear.

Who Took Part

By PubMed's age tags, the people studied were adults, men only.

The study was carried out in an outpatient clinic.

Nineteen overweight (body mass index 32.1 +/- 0.9 kg/m(2)) men participated.

How the Study Was Run

In design terms this was a randomized and crossover study.

The participants were allocated by chance, so the Ghrelin group and the comparison group should start out alike.

Each person switched between Ghrelin and the comparison at some point, usually with a gap in between.

This is a randomized cross-over study of four orally consumed preloads followed by blood sampling (+15, 30, 45, 60, 90, 120, 180 min), then a buffet meal.

What Was Measured

PubMed files the paper under topics including Acetaminophen, Amino Acids, Analgesics, Non-Narcotic, Blood Glucose, Caseins, Cholecystokinin and Diet.

What This Means in Plain Language

The paper is a randomized and crossover study of Ghrelin and Cholecystokinin (CCK).

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2006 (The Journal of clinical endocrinology and metabolism), a journal based in United States.

More context: the Ghrelin compound page and the Cholecystokinin (CCK) compound page, all human trials.