Obese subjects respond to the stimulatory effect of the ghrelin agonist growth hormone-releasing peptide-2 on food intake

What Was Tested

Researchers studied Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and Ghrelin in this randomized controlled trial publication.

Who Took Part

The age groups tagged for this paper are teenagers and adults, both men and women.

Before lunch, subjects received taped instructions to eat as much as they wanted.

How the Study Was Run

In design terms this was a randomized, double-blind and placebo-controlled study.

The participants were allocated by chance, so the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group and the comparison group should start out alike.

Blinding on both sides kept the participants and researchers unaware of who received Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Some participants received a placebo instead of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), giving a reference point.

Blood for hormone assays was collected through an intravenous forearm catheter.

Hunger and fullness were rated on visual analog scales before and after a fixed breakfast (320 kcal at 120 minutes) and a buffet lunch at 240 minutes.

What Was Measured

The subject headings attached to it are Appetite, Eating, Food, Ghrelin, Hormones, Human Growth Hormone and Hunger.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and Ghrelin.

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2006 (Obesity (Silver Spring, Md.)), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page and the Ghrelin compound page, all human trials.