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Final height outcome after three years of growth hormone and gonadotropin-releasing hormone agonist treatment in short adolescents with relatively early puberty.

Plain-language guide to PMID 17284626 (2007): randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 12 girls.

Key Facts

PMID
17284626
Journal
The Journal of clinical endocrinology and metabolism
Year
2007
Study type
Randomized Controlled Trial
Authors
van Gool SA et al. (12 authors)
DOI
10.1210/jc.2006-2272

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), published as a randomized controlled trial.

Their objective was to assess final height (FH) and adverse effects of combined GH and GnRH agonist (GnRHa) treatment in short adolescents born small for gestational age or with normal birth size (idiopathic short stature).

Who Took Part

According to the abstract, 12 girls were involved.

The age groups tagged for this paper are children and teenagers, both men and women.

How the Study Was Run

The design is described as randomized.

Random assignment meant chance, not the researchers, decided who got Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and who got the comparison, which limits bias.

FH was assessed at the age of 18 yr or older in girls or 19 yr or older in boys.

What Was Measured

PubMed files the paper under topics including Body Height, Follicle Stimulating Hormone, Gonadotropin-Releasing Hormone, Human Growth Hormone, Puberty, Precocious, Regression Analysis and Reproducibility of Results.

What This Means in Plain Language

The paper is a randomized study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 12 girls.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2007 (The Journal of clinical endocrinology and metabolism), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.