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Brain indices of nicotine's effects on attentional bias to smoking and emotional pictures and to task-relevant targets.
Plain-language guide to PMID 17365767 (2007): double-blind randomized controlled trial of Therapeutic nicotine (patch, non-peptide).
Key Facts
- PMID
- 17365767
- Journal
- Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
- Year
- 2007
- Study type
- Randomized Controlled Trial
- Authors
- Gilbert DG et al. (6 authors)
- DOI
- 10.1080/14622200701188810
What This Study Did, in Plain Language
What Was Tested
Researchers studied Therapeutic nicotine (patch, non-peptide) in this randomized controlled trial publication.
Aversive and smoking-related stimuli are related to smoking urges and relapse and can be potent distractors of selective attention.
The researchers assessed the effect of nicotine on distraction by emotionally negative, positive, neutral, and smoking-related pictures immediately preceding target digits during a rapid visual information processing task in 16 smokers in a double-blind, counterbalanced, within-subjects design.
Who Took Part
PubMed indexes the participants as adults, both men and women.
How the Study Was Run
In design terms this was a randomized, double-blind and placebo-controlled study.
Random assignment meant chance, not the researchers, decided who got Therapeutic nicotine (patch, non-peptide) and who got the comparison, which limits bias.
As a double-blind Therapeutic nicotine (patch, non-peptide) study, the assignments were hidden from both participants and investigators until the end.
The comparison arm used a placebo, so changes seen with Therapeutic nicotine (patch, non-peptide) could be set against what happens without it.
What Was Measured
The researchers assessed the effect of nicotine on distraction by emotionally negative, positive, neutral, and smoking-related pictures immediately preceding target digits during a rapid visual information processing task in 16 smokers in a double-blind, counterbalanced, within-subjects design.
The subject headings attached to it are Affect, Brain, Cues, Electroencephalography, Ganglionic Stimulants, Nicotine and Reaction Time.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Therapeutic nicotine (patch, non-peptide).
The publication is from 2007 (Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco), a journal based in England.
More context: the Therapeutic nicotine (patch, non-peptide) compound page, all human trials.
Our Notes on the Compound
Therapeutic nicotine (patch, non-peptide): Pure nicotine as a signaling tool, separated from smoking and vaping.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.