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[Therapeutic effects of acupoint injection at cervical Jiaji points and effects on ET and CGRP in the patient of ischemic stroke]

Plain-language guide to PMID 17370487 (2007): randomized controlled trial of CGRP (Calcitonin Gene-Related Peptide).

Key Facts

PMID
17370487
Journal
Zhongguo zhen jiu = Chinese acupuncture & moxibustion
Year
2007
Study type
Randomized Controlled Trial
Authors
Wang XL et al. (5 authors)

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of CGRP (Calcitonin Gene-Related Peptide), published as a randomized controlled trial.

To observe effects of point injection at cervical Jiaji points on endothelin (ET) and calcitonin gene related peptide (CGRP) in the patient of ischemic stroke (IS).

Who Took Part

The age groups tagged for this paper are adults, middle-aged adults and older adults, both men and women.

Seventy cases of IS were randomly divided into a treatment group of 35 cases and a control group of 35 cases.

The treatment group were treated with acupoint injection at cervical Jiaji points and routine acupuncture, and the control group only with routine acupuncture.

How the Study Was Run

In design terms this was a randomized study.

Because people in this CGRP (Calcitonin Gene-Related Peptide) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Two weeks constituted one course with an interval of one day between courses.

After two courses and 4 courses, changes of ET and CGRP were detected, and after 4 courses, their clinical therapeutic effects were evaluated.

What Was Measured

The subject headings attached to it are Acupuncture Points, Brain Ischemia, Calcitonin Gene-Related Peptide, Cervical Vertebrae, Drugs, Chinese Herbal, Endothelins and Injections.

What This Means in Plain Language

The paper is a randomized study of CGRP (Calcitonin Gene-Related Peptide).

Results are reported in around 2 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2007 (Zhongguo zhen jiu = Chinese acupuncture & moxibustion), a journal based in China.

More context: the CGRP (Calcitonin Gene-Related Peptide) compound page, all human trials.

Our Notes on the Compound

CGRP (Calcitonin Gene-Related Peptide): A 37-amino-acid neuropeptide that widens blood vessels and is involved in migraine; given in research provocation studies.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.