Performance of cryopreserved pre-embryos obtained in in vitro fertilization cycles with or without a gonadotropin-releasing hormone agonist.

What Was Tested

The paper reports a study of Gonadotropin-Releasing Hormone and Follicle Stimulating Hormone, published as a clinical trial.

To evaluate the viability and potential for pregnancy of cryopreserved/thawed pre-embryos obtained after ovarian stimulation using gonadotropin-releasing hormone agonist (GnRH-a) adjunct therapy.

Who Took Part

The age groups tagged for this paper are adults, women only.

Retrospective clinical evaluation of all patients receiving a gonadotropin ovarian stimulation protocol (follicle-stimulating hormone/human menopausal gonadotropin [FSH/hMG]) with/without GnRH-a.

Patients receiving leuprolide acetate (LA)/FSH/hMG (n = 136: LA in the luteal phase; long protocol) were compared with patients receiving FSH/hMG alone (n = 130) within the same time-frame in their program (April 1987 through October 1989).

How the Study Was Run

Academic tertiary clinical care unit.

All patients had both a cycle in which pre-embryos were transferred fresh and a cycle of thaw of cryopreserved pre-embryos (frozen at the pronuclear stage in a slow freeze-thaw protocol using 1,2 propanediol) transferred in monitored natural cycles.

What Was Measured

Topics PubMed links to this paper include Blastocyst, Cryopreservation, Fertilization in Vitro, Follicle Stimulating Hormone, Gonadotropin-Releasing Hormone, Menotropins and Menstrual Cycle.

What This Means in Plain Language

This is a clinical trial of Gonadotropin-Releasing Hormone and Follicle Stimulating Hormone.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 1992 (Fertility and sterility), a journal based in United States.

More context: all human trials.