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Second meal effects of dietary calcium and vitamin D.
Plain-language guide to PMID 17522603 (2008): crossover randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 17522603
- Journal
- European journal of clinical nutrition
- Year
- 2008
- Study type
- Randomized Controlled Trial
- Authors
- Soares MJ et al. (2 authors)
- DOI
- 10.1038/sj.ejcn.1602803
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.
To determine the second meal effects of calcium and vitamin D on postprandial glucose, insulin, non-esterified fatty acids (NEFA) and glycerol.
Who Took Part
By PubMed's age tags, the people studied were middle-aged adults, both men and women.
Eight volunteers aged (mean+/-s.e.m.) 55.5+/-1.2 years and body mass index 29.0+/-1.6 kg/m(2), completed a randomized within-subject design that compared a low calcium-low vitamin D breakfast and an isocaloric high calcium-high vitamin D breakfast (HCB).
How the Study Was Run
The researchers set it up as a randomized and crossover study.
Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
Each person switched between Vitamin D, K2, Magnesium and Zinc and the comparison at some point, usually with a gap in between.
Four hours following each breakfast, a very low calcium standard lunch was ingested.
Serial blood collections were made on the hour over a duration of 8 h.
Postprandial responses were calculated as the percentage change (Delta) from the fasting value for breakfast meals, and the 4th hour breakfast value for each lunch, respectively.
What Was Measured
Topics PubMed links to this paper include Area Under Curve, Blood Glucose, Body Mass Index, Bone Density Conservation Agents, Calcium, Calcium, Dietary and Fatty Acids, Nonesterified.
What This Means in Plain Language
The paper is a randomized and crossover study of Vitamin D, K2, Magnesium and Zinc.
Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2008 (European journal of clinical nutrition), a journal based in England.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.