Exposure to human chorionic gonadotropin during in vitro maturation does not improve the maturation rate and developmental potential of immature oocytes from patients with polycystic ovary syndrome

What Was Tested

The paper reports a study of hCG (human chorionic gonadotropin), published as a randomized controlled trial.

To investigate the effects of human chorionic gonadotropin (hCG) in culture medium on the in vitro maturation (IVM) and subsequent developmental potential of human immature oocytes.

Who Took Part

According to the abstract, 62 women were involved.

By PubMed's age tags, the people studied were adults, women only.

62 women with polycystic ovary syndrome (PCOS) undergoing IVM treatment.

Immature oocytes were retrieved from unstimulated ovaries of women with PCOS.

How the Study Was Run

The researchers set it up as a randomized study.

The women were allocated by chance, so the hCG (human chorionic gonadotropin) group and the comparison group should start out alike.

Reproductive Medicine Center, First Affiliated Hospital of Wenzhou Medical College, People's Republic of China.

The researchers tried three different culture systems in this experiment.

In group C, oocytes were cultured only in hCG-free IVM medium.

After the oocytes had matured in vitro, fertilization and embryo transfer were performed.

What Was Measured

PubMed files the paper under topics including Cell Culture Techniques, Chorionic Gonadotropin, Culture Media, Embryo Culture Techniques, Embryo Implantation, Embryo Transfer and Fertility Agents, Female.

What This Means in Plain Language

The paper is a randomized study of hCG (human chorionic gonadotropin) in 62 women.

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2008 (Fertility and sterility), a journal based in United States.

More context: the hCG (human chorionic gonadotropin) compound page, all human trials.