Salmon calcitonin treatment by nasal spray in primary hyperparathyroidism

What Was Tested

Researchers studied Calcitonin in the context of hyperparathyroidism in this randomized controlled trial publication.

Who Took Part

According to the abstract, 12 patients were involved.

By PubMed's age tags, the people studied were adults, middle-aged adults and older adults, both men and women.

How the Study Was Run

The design is described as randomized and double-blind.

Because people in this Calcitonin study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Neither the patients nor the staff measuring them knew who was on Calcitonin, so expectations could not easily colour the readings.

The concentration of ionized calcium in whole blood (B-Ca++), serum phosphate (S-P), magnesium (S-Mg), plasma sCT (Pl-sCT), and endogenous CT (hCT) was followed during five 24-hour periods with at least three days between.

What Was Measured

PubMed files the paper under topics including Analysis of Variance, Calcitonin, Calcium, Hyperparathyroidism, Magnesium, Phosphates and Radioimmunoassay.

What This Means in Plain Language

The paper is a randomized and double-blind study of Calcitonin in 12 patients in people with hyperparathyroidism.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 1991 (Bone), a journal based in United States.

More context: the Calcitonin compound page, Hyperparathyroidism research.