Effect of calcium and vitamin D supplementation on bone mineral density in children with inflammatory bowel disease.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this controlled clinical trial publication.

The purpose of this study was to evaluate the effect of calcium and vitamin D2 supplementation on bone mineral density (BMD) in children with inflammatory bowel disease (IBD).

Who Took Part

The study group was 20 boys.

PubMed indexes the participants as children, both men and women.

Seventy-two patients were divided into 2 groups based on lumbar spine areal BMD (L2-4 aBMD).

Patients with an L2-4 aBMD z score of -1 or higher were assigned to the control group (n = 33; mean age, 11.0 +/- 3.5 years; 20 boys).

How the Study Was Run

The design is described as open-label.

Nothing was hidden in this open-label Vitamin D, K2, Magnesium and Zinc study: the boys and staff both knew the treatment.

What Was Measured

PubMed files the paper under topics including Absorptiometry, Photon, Bone Density, Bone Density Conservation Agents, Calcium, Cohort Studies, Dietary Supplements and Ergocalciferols.

What This Means in Plain Language

The paper is an open-label study of Vitamin D, K2, Magnesium and Zinc in 20 boys.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2007 (Journal of pediatric gastroenterology and nutrition), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.