Vitamin D status and response to Vitamin D(3) in obese vs. non-obese African American children.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a clinical trial.

To examine serum 25(OH)D in obese (BMI >95th percentile for age) vs. non-obese (BMI = 5th-75th percentile for age) 6-10-year-old African American children and compare their differences in therapeutic response to vitamin D supplementation.

Why It Was Studied

Serum 25-hydroxyvitamin D (25(OH)D) is low in obese adults.

Who Took Part

PubMed indexes the participants as children, both men and women.

How the Study Was Run

The researchers set it up as an open-label study.

Being open-label, the Vitamin D, K2, Magnesium and Zinc study did not mask who received what.

Serum 25(OH)D, 1,25-dihydroxyvitamin D (1,25(OH)(2)D), parathyroid hormone (PTH), leptin, and markers of bone turnover (serum bone-specific alkaline phosphatase (BSAP), osteocalcin (OC), and urine n -telopeptide cross-links of type 1 collagen (urine NTX)) were measured.

Vitamin D deficiency was defined as serum 25(OH)D < or =20 ng/ml and insufficiency as 21-29 ng/ml respectively.

What Was Measured

PubMed files the paper under topics including Black or African American, Alkaline Phosphatase, Bone and Bones, Collagen Type I, Dietary Supplements, Leptin and Obesity.

What This Means in Plain Language

The paper is an open-label study of Vitamin D, K2, Magnesium and Zinc.

Results are reported in around 3 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2008 (Obesity (Silver Spring, Md.)), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.