← Human Trials & Peer-Reviewed Studies
Black and white female adolescents lose vitamin D metabolites into urine.
Plain-language guide to PMID 18414066 (2008): crossover randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 18414066
- Journal
- The American journal of the medical sciences
- Year
- 2008
- Study type
- Randomized Controlled Trial
- Authors
- Thierry-Palmer M et al. (7 authors)
- DOI
- 10.1097/MAJ.0b013e31815768db
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.
The black American population has a higher prevalence of salt sensitivity compared with the white American population.
Dahl salt-sensitive rats, models of salt-induced hypertension, excrete protein-bound vitamin D metabolites into urine, a process that is accelerated during high salt intake.
Who Took Part
PubMed indexes the participants as children and teenagers, both men and women.
How the Study Was Run
The researchers set it up as a randomized and crossover study.
Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
In the crossover set-up each of the participants took both Vitamin D, K2, Magnesium and Zinc and the comparison in turn, acting as their own control.
What Was Measured
The researchers tested the hypothesis that urinary vitamin D metabolite content and 25-hydroxyvitamin D (25-OHD) binding activity of black female adolescents would be greater than that of white female adolescents.
PubMed files the paper under topics including 24,25-Dihydroxyvitamin D 3, Black or African American, Sodium Chloride, Dietary, Vitamin D and White People.
What This Means in Plain Language
The paper is a randomized and crossover study of Vitamin D, K2, Magnesium and Zinc.
Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2008 (The American journal of the medical sciences), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.