Diffuse musculoskeletal pain is not associated with low vitamin D levels or improved by treatment with vitamin D.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

Comparison of vitamin D levels in patients with diffuse musculoskeletal pain with controls; evaluation of the effect of treatment with vitamin D on diffuse pain.

Who Took Part

By PubMed's age tags, the people studied were adults, middle-aged adults and older adults, both men and women.

25-Hydroxyvitamin D levels were measured in patients with diffuse musculoskeletal pain and osteoarthritis (controls) recruited from a community rheumatology practice.

How the Study Was Run

In design terms this was a randomized, double-blind and placebo-controlled study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

Outcomes assessed were pain measured by visual analog scale (VAS) and functional pain score (FPS).

What Was Measured

PubMed files the paper under topics including Case-Control Studies, Ergocalciferols, Fibromyalgia, Osteoarthritis, Pain, Pain Measurement and Vitamin D Deficiency.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2008 (Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.